Jorgenson's research focuses on the human dimensions of global environmental change, with a focus on the drivers of greenhouse gas emissions, energy consumption, industrial pollution and land cover change. Jorgenson also conducts research on the political-economic and environmental conditions that shape population health outcomes, uneven development, income inequality and environmental concern. Jorgenson's ongoing collaborative research on the facility-level and country-level factors that shape power plants’ carbon emissions has received multiple waves of funding from the National Science Foundation. Jorgenson's published work appears in a variety of journals, including American Journal of Sociology, Nature Climate Change, Social Forces, Environmental Research Letters, Sociological Theory, Social Problems, Sustainability Science, Sociological Science, Climatic Change, Social Science Research, WIREs Climate Change, Sociological Forum, Ecological Economics, SSM Population Health, and Conservation Biology. Jorgenson recently finished a book with coauthors Don Grant and Wesley Longhofer, titled Super Polluters: Tackling the World’s Largest Sources of Climate-Disrupting Emissions, which will be published by Columbia University Press in 2020. Jorgenson was the 2016-2017 chair of the Environmental Sociology Section of the American Sociological Association (ASA), and a member of the ASA’s Task Force on Sociology and Global Climate Change, which concluded in 2016. Jorgenson served as the 2018-2019 chair of the Sociology of Development Section of the ASA and is currently an at large officer for the Society for Human Ecology. Jorgenson is the founding co-editor of Sociology of Development, a journal published by University of California Press.