While Woodruff has a great interest in public policy, his formal training is as an immunology bench researcher specializing in vaccination response. Immune responses to vaccination are highly complex, but follow a strict set of rules that guide the development of a protective immune response. His research seeks to understand those rules in detail, and apply that understanding to the development of increasingly effective vaccines in the future.
In addition to bench research, Woodruff has been involved in a number of scientific outreach efforts attempting to direct high-level scientific knowledge towards a lay-audience. Recently, this interest in scientific outreach has led to an interest, and subsequent involvement in vaccine policy debate.
Describes some described some of the earliest immune-cell dynamics that initiate the immune response to influenza vaccination.
Identifies a subset of cells within the lymph node that are critical in supporting the development of antibody responses to vaccination.
Describes and tries to quantify the fluid exchange that occurs between the blood and lymphatic systems within the lymph node.